Hesperidin

Product Name: Hesperidin

Active Ingredient: Hesperidin

Source:Citrus sinensis

Specification:90%,95%

Test Method:HPLC

Appearance: Greyish-yellow or light yellow hygroscopic powder

Partical Size:95% pass 80mesh

Staherb Hesperidin Description:

Hesperidin is a plant chemical that is classified as a “bioflavonoid”. It is found primarily in citrus fruits.

Hesperidin alone, or in combination with other citrus bioflavonoids( Diosmin , for example), is most often used for blood vessel conditions such as hemorrhoids, various vein, and poor circulation (venous stasis). It is also used to treat lymphedema, a condition involving fluid.

Hesperidin is a flavone-on glycoside found in citrus fruits. Its aglycone form is called hesperetin. Its name is derived from the word "hesperidium", for fruit produced by citrus trees.

It was first isolated in 1828 by French chemist Lebreton from the white inner layer of citrus peels (mesocarp, albedo). It is Hesperidin is believed to play a role in plant defense.

Hesperidin is a naturally occurring bioflavonoid, a compound in plants with antioxidant properties. Bioflavonoids also provide the color, flavor and aroma to plants. While hesperidin and other similar bioflavonoids are commonly referred to as vitamin P, they are not actual vitamins. Hesperidin does not naturally occur in the body; you can only get it through foods or synthetic supplements.

 

Citrus aurantium extract

Active

Ingredients

Specs

Test Method

Appearance

Solubility

Synephrine

6%-30%

HPLC

Brown-yellow powder

Slightly soluble

in water and

methanol

Hesperidin

10%-98%

HPLC

Yellow to light brown powder

Slightly soluble

in methanol

Hesperetin

10%-98%

HPLC

Yellow to dark brown powder

Slightly soluble

in water and

methanol

Neohesperidin

10%-98%

HPLC

Off-White or light

yellow powder

soluble in hot

water and

ethanol

Diosmin/

Hesperidin

9:1

HPLC

Grayish Yellow or 

yellow powder

Slightly soluble

in water

Citrus Bioflavonoids

10%-90%

HPLC

Brown-yellow powder

Slightly soluble

in water

Nobiletin

98%

HPLC

White Crystalline 

powder

soluble in hot

water and

ethanol

PMFs

(Polymethoxy

Flavones)

10%-98%

HPLC

Yellow to Brown

Partially soluble in hot water and ethanol

NHDC

98%

HPLC

White

soluble in water

Citrus

Polyphenols

10%-90%

HPLC

Yellow to Brown 

soluble in water

 

Staherb Hesperidin Function:

1. For poor circulation in the legs (chronic venous insufficiency, CVI);

2. Synergistic with Vitamin C, enhance the function;

3. Prevent hemorrhoids from coming back after they have healed;

4. Enhance cardiovascular , improve microcirculation;

5. Increased capillary toughness;

6. Prevention of microvascular rupture and bleeding;

7. Adjuvant therapy for hypertension.

 

Staherb Hesperidin Application:

1. Mainly used for raw material of pharmaceutical tablets and caps;

2. Raw material of diosmin and methyl hesperidin etc;

3. Combined with diosmin  for medicine;

4. Used for eye cream which help treat dark under eye circles.

 

For more product information pls kindly contact email sales09@staherb.cn

Reference:

 

  1. 1.

    E. Middleton, Int. J. Pharmacognosy439, 175 – 182 (1996).

  2. 2.

    A. S. Saraf, and É. T. Oganesyan, Khim.-Farm. Zh.25(2), 4 – 8 (1991).

  3. 3.

    D. Yu. Korul’kin, Natural Flavonoids, Siberian Branch, Russian Academy of Sciences, Novosibirsk; Geo Academic Press, Institute of Organic Chemistry, Novosibirsk (2007), pp. 191 – 220.

  4. 4.

    T. Brasseur, Pharm. Belg.44(6), 403 – 410 (1989).

  5. 5.

    O. Benavente-Garcia, J. Castillo, F. R. Marin, et al., Agr. Food Chem.45(12), 4506 – 4514 (1997).

  6. 6.

    B. S. G. Winkel, The Science of Flavonoids, Columbus, Ohio (2006), pp. 47 – 71.

  7. 7.

    Medicines Manufactured by Foreign Firms in Russia [in Russian], AstraFarmservis, Moscow (1993).

  8. 8.

    J. Cha and Y. Cho, Hanguk Nonghwa Hakhoechi40(6), 577 – 582 (1997).

  9. 9.

    I. Nouya, A. Shigery, O. Yosheshico, et al., Carbohydrates43(11), 1212 – 1218 (1996).

  10. 10.

    F. Smith and H. C. Srivastava, J. Amer. Chem. Soc.78, 1404 (1956).