1. 迷迭香酸rosmarnic aicd

迷迭香酸

品名:迷迭香提取物

拉丁名:Rosmarinus officinalis L

Cas 號.:20283-92-5

規格:5%

有效成分:迷迭香酸

顏色:棕黃色精細粉末

檢測方式:HPLC

迷迭香酸（Rosmarinicacid，簡稱RosA）是從唇形科植物迷迭香中分離得到的一種水溶性的天然酚酸類化合物，分布較為廣氾，主要存在於唇形科、紫草科、葫蘆科、椴樹科、傘形科的多種植物中，尤以唇型科和紫草科植物中含量 。 迷迭香酸是一種天然抗氧化劑，具有較強的抗氧化活性，有助于防止自由基造成的細胞受損，因此降低了癌症和動脈硬化的風險。迷迭香酸具有較強的抗炎活性，同時迷迭香酸還具有抗菌、抗病毒、抗腫瘤的活性。目前，迷迭香酸在製藥、食品、化妝品等領域中已體現出其重要的應用價值。

 

【產品名稱】　迷迭香酸 Rosmarinic acid

【化學名稱】  [R(E)]α-[[3-(3,4-二羥基苯基)-l-氧代-2-丙烯基]氧基]-3，4-二羥基苯丙酸.[4aR-(4aa,9b,10a,10ab)]-1,3,4,9,10,10a-Hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-2H-10,4a-(epoxymethano)phenanthren-12-one

【CAS   名】   20283-92-5

 【溶 解 度】易溶于水及乙醇水溶液，不溶于油脂、 。

【其他性質】 迷迭香酸是一種含多酚羥基的酸，

【來    源】主要來源於唇形科植物迷迭香（Rosmarinus officinalis）

【產品特性】：從植物迷迭香中提取的一種水溶性酚酸類化合物，植物中芳香物質的一種，同時也是優質的 水溶性抗氧化劑。
【性狀】棕色至純白色粉末 
【功能】抗氧化作用；廣譜抑菌功效；抗炎、抗病毒、抗腫瘤活性；抗紫外線、抗過敏作用。
用途：廣氾應用於食品、保健品、醫藥、調味品和日用化工業等領域。

References參考文獻:

Achnine L, Blancaflor EB, Rasmussen S, Dixon RA (2004) Colocalization of L-phenylalanine ammonia-lyase and cinnamate 4-hydroxylase for metabolic channeling in phenylpropanoid biosynthesis. Plant Cell 16:3098–3109

 

  1. China Pharmacopoeia Committee (2010) Chinese Pharmacopoeia of People’s Republic of China. Chemical Industry, Beijing, p 71

  2. Cukovic D, Ehlting J, van Ziffle JA, Douglas CJ (2001) Structure and evolution of 4-coumarate: coenzyme A ligase (4CL) gene families. J Biol Chem 382:645–654

  3. Dean C, Schmidt R (1995) Plant genomes: a current description. Annu Rev Plant Physiol Plant Mol Biol 46:395–418

  4. Dixon RA, Paiva NL (1995) Stress-induced phenylpropanoid metabolism. Plant Cell 7:1085–1097

  5. Dong J, Wan G, Liang Z (2010) Accumulation of salicylic acid-induced phenolic compounds and raised activities of secondary metabolic and antioxidative enzymes in Salvia miltiorrhiza cell culture. J Biotechnol 148:99–104

  6. Franklin AE, Cande WZ (1999) Nuclear organization and chromosome segregation. Plant Cell 11:523–534

  7. Fukunaga K, Fujikawa Y, Esaka M (2010) Light regulation of ascorbic acid biosynthesis in rice via light responsive cis-elements in genes encoding ascorbic acid biosynthetic enzymes. Biosci Biotechnol Biochem 74:888–891

  8. Gilmartin PM, Sarokin L, Memelink J, Chua NH (1990) Molecular light switches for plant genes. Plant Cell 2:369–378

  9. Halliday KJ, Fankhauser C (2003) Phytochrome-hormonal signalling networks. New Phytol 157:449–463

  10. Huang B, Duan Y, Yi B, Sun L, Lu B, Yu X, Sun H, Zhang H, Chen W (2008a) Characterization and expression profiling of cinnamate 4-hydroxylase gene from Salvia miltiorrhiza in rosmarinic acid biosynthesis pathway. Russ J Plant Physiol 5:431–440

  11. Huang B, Yi B, Duan Y, Sun L, Yu X, Guo J, Chen W (2008b) Characterization and expression profiling of tyrosine aminotransferase gene from Salvia miltiorrhiza (Dan-shen) in rosmarinic acid biosynthesis pathway. Mol Biol Rep 35:601–612

  12. Ibraheem O, Botha CE, Bradley G (2010) In silico analysis of cis-acting regulatory elements in 5′ regulatory regions of sucrose transporter gene families in rice (Oryza sativa japonica) and Arabidopsis thaliana. Comput Biol Chem 34:268–283

  13. Kim KH, Janiak V, Petersen M (2004) Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. Plant Mol Biol 54:311–323

  14. Liu AH, Li L, Xu M, Lin YH, Guo HZ, Guo DA (2006) Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method. J Pharm Biomed Anal 41:48–56

  15. Ma L, Zhang X, Guo H, Gan Y (2006) Determination of four water-soluble compounds in Salvia miltiorrhiza Bunge by high-performance liquid chromatography with a coulometric electrode array system. J Chromatogr B Analyt Technol Biomed Life Sci 833:260–26

  16. Minami E, Ozeki Y, Matsuoka M, Koiruka N, Tanaka Y (1989) Structure and some characterization of the gene for phenylalanine ammonia-lyase from rice plants. Eur J Biochem 185:19–25

  17. Petersen M (2007) Current status of metabolic phytochemistry. Phytochemistry 68:2847–2860

  18. Petersen M, Simmonds MS (2003) Rosmarinic acid. Phytochemistry 62:121–125

  19. Petersen M, Haüsler E, Karwatzki B, Meinhard J (1993) Proposed biosynthetic pathway for rosmarinic acid in cell cultures of Coleus blumei Benth. Planta 189:10–14

  20. Petersen M, Abdullah Y, Benner J, Eberle D, Gehlen K, Hücherig S, Janiak V, Kim KH, Sander M, Weitzel C, Wolters S (2009) Evolution of rosmarinic acid biosynthesis. Phytochemistry 70:1663–1679

  21. Rischer H, Oresic M, Seppanen-Laakso T, Katajamaa M, Lammertyn F, Ardiles-Diaz W, van Montagu MC, Inze D, Oksman-Caldentey KM, Goossens A (2006) Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells. Proc Natl Acad Sci USA 103:5614–5619 

  22. Rombauts S, Déhais P, van Montagu M, Rouzé P (1999) PlantCARE, a plant cis-acting regulatory element database. Nucl Acids Res 27:295–296

  23. Singh KB, Foley RC, Onate-Sánchez L (2002) Transcription factors in plant defence and stress responses. Curr Opin Plant Biol 5:430–436

  24. Song J, Wang Z (2009) Molecular cloning, expression and characterization of a phenylalanine ammonia-lyase gene (SmPAL1) from Salvia miltiorrhiza. Mol Biol Rep 36:939–952

  25. Song J, Wang Z (2011) RNAi-mediated suppression of the phenylalanine ammonia-lyase gene in Salvia miltiorrhiza causes abnormal phenotypes and a reduction in rosmarinic acid biosynthesis. J Plant Res 124:183–192

  26. Wang H, Ma LG, Li JM, Zhao HY, Deng XW (2001) Direct interaction of Arabidopsis cryptochromes with COP1 in light control development. Science 294:154–158

  27. Wyeth WW, Albin S (2004) Applied bioinformatics for the identification of regulatory elements. Nat Rev Genet 5:276–287

  28. Xiao Y, Gao S, Di P, Chen J, Chen W, Zhang L (2009) Methyl jasmonate dramatically enhances the accumulation of phenolic acids in Salvia miltiorrhiza hairy root cultures. Physiol Plant 137:1–9

  29. Yan Q, Shi M, Ng J, Wu JY (2006) Elicitor-induced rosmarinic acid accumulation and secondary metabolism enzyme activities in Salvia miltiorrhiza hairy roots. Plant Sci 170:853–858

  30. Zhang Y, Yan Y, Wang Z (2010) The Arabidopsis PAP1 transcription factor plays an important role in the enrichment of phenolic acids in Salvia miltiorrhiza. J Agric Food Chem 58:12168–12175

  31. Zhao SJ, Hu ZB, Liu D, Leung FC (2006) Two divergent members of 4-coumarate:coenzyme A ligase from Salvia miltiorrhiza Bunge: cDNA cloning and functional study. J Integr Plant Biol 48:1355–1364

  32. Zhou L, Zuo Z, Chow MS (2005) Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol 45:1345–1359

回到頂部
桌面版