Product Name: Gotu Kola Extract
Latin Name: Centella Asiatica(L.) Urban
Product Specification:
Total Triterpenoid glycosides 10%- 80%
Madecassoside 90%-95%
Asiaticoside(s) 10%, 20%, 30%, 40%, 50%, 60%, 90% , 95%HPLC
Madecassic Acid 95%
Asiatic Acid 95% HPLC
Product Type: Green Brown Powder
Part of the Plant Used: Herb(Dried, 100% Natural)
Extract Method: Grain Alcohol/water
積雪草提取物中含有多種三萜類,其中包含α-香樹脂醇結構。主要成分為積雪草甙,羥基積雪草甙,外觀棕黃色至白色精細粉末,口感微苦。對於治療濕熱黃疸,中暑腹瀉,砂淋血淋,癰腫瘡毒,跌扑損傷都有極好的效果。
積雪草提取物及積雪草經常被外用於祛疤痕促進傷口癒合
資料顯示,積雪草又叫雷公根,屬於多年生草本匍匐植物。因其葉子酷似馬蹄狀或半個銅錢,又稱“馬蹄草”、“連錢草”。原產于印度,喜生于濕潤的河岸、沼澤、草地中。現已廣氾分布于熱帶、亞熱帶區,中國也有,主要分布于長江以南各省。
我國應用積雪草的曆史極其悠久, 古籍《神農本草經》就有記載積雪草對於清熱解毒、利濕消腫等方面的藥用功效。在中國和印度,積雪草經常被外用於祛疤痕、促進傷口癒合。隨着科技的進步以及人皆有之的愛美之心,積雪草提取物開始在護膚品、化妝品等領域被廣氾使用。
積雪草中的有效成分 1948 年就已分離出來,是一系列三萜類化合物,包含了皂苷元(積雪草酸和羥基積雪草酸) ,還有它們的儲存形式葡萄糖甙(積雪草苷、羥基積雪草苷)。此外,積雪草中還有多酚以及黃酮類化合物。正是由於積雪草中的這些化學成分,使得積雪草提取物具有多種功效。與積雪草有關的成分有:積雪草根提取物、積雪草花/葉/莖提取物、積雪草提取物、積雪草葉提取物、積雪草苷。
上禾生物積雪草提取物中的有效成分主要是積雪草苷和羥基積雪草苷,而關於積雪草祛疤痕、促進傷口癒合等作用已經有几千年的曆史了。現代研究表明,積雪草相關提取物有促進皮膚纖維細胞生長、促進皮膚膠原合成、抑制炎症、抑制基質金屬蛋白酶活性的作用。所以積雪草對皮膚有損傷修復、減緩皮膚潰爛、祛疤修復、促進衰老肌膚新生、祛除妊娠紋等功效。
產品詳詢:13657416805
產品文獻:
1.Berg, J., T. John, and L. Stryer. 2001. Biochemistry. Freeman WH and Co., New York
2.Bonfill, M., S. Mangas, R.M. Cusidü, L. Osuna, M.T. Piñol, and J. Palazün. 2006. Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry. Biomed. Chromatogr. 20:151–153.
3.Bonner, J. 1972. The isoprenoids, p. 665–690. In: J. Bonner and J.E. Varner (eds.). Plant biochemistry. Academic Press, New York.
4.Gunther. B. and H. Wagner. 1996. Quantitative determination of triterpenes in extracts and phytoparations of Centella asiatica (L.) Urban. Phytomedicine 3:59–65.
5.Hsu, Y.L., P.L. Kuo, L.T. Lin, and C.C. Lin. 2005. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells. J. Pharmacol. Exp. Ther. 313:333–344.
6.Inamdar, P.K., R.D. Yeole, A.B. Ghogare, and N.J. Souza. 1996. Determination of biologically active constituents in Centella asiatica. J. Chromatogr. A 742:127–130.
7.Jian, Z., L.C. Davis, and R. Verpoorte. 2005. Elicitor signal transduction leading to production of plant secondary metabolites. Biotechnol. Adv. 23:283–333.
8.Joshi, S.G. 2000. Medicinal plants. Oxford & IBH Publishing Co., Pvt, Ltd., New Delhi, India.
9.Kiong, A.L.P., M. Mahmood, N.M. Fadzillah, and S.K. Daud. 2005. Effects of precursor supplementation on the production of triterpenes by Centella asiatica callus cultures. Pak. J. Biol. Sci. 8:1160–1169
10.Memon, A.R., Q.Y. Chen, and W.F. Boss. 1989. Inositol phospholipids activate plasma membrane ATPase in plants. Biochem. Biophys. Res. Commun. 162:1295–1301
11.Nelson, D.L. and M.M. Cox. 2001. Lehninger’s principles of biochemistry. Freeman WH and Co., New York. p. 1040–1059.
12.Park, B.C., K.O. Bosire, E.S. Lee, Y.S. Lee, and J.A. Kim. 2005. Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells. Cancer Lett. 218:81–90.
13.Perassolo, M., C. Quevedo, V. Busto, F. Ianone, A.M. Giulietti, and J. Rodriguez Talou. 2007. Enhance of anthraquinone production by effect of proline and aminoindan-2-phosphonic acid in Rubia tinctorum suspension cultures. Enzyme Microb. Technol. 41:181–185.
14.Schaneberg, B.T., J.R. Mikell, E. Bedir, and I.A. Khan. 2003. An improved HPLC method for quantitative determination of six triterpenes in Centella asiatica extracts and commercial products. Pharmazie 58:381–384.
15.Seidel, V., J. Windhövel, G. Eaton, A.W. Alfermann, R.R. Arroo, M. Medarde, M. Petersen, and J.G. Woolley. 2002. Biosynthesis of podophyllotoxin in Linum album cell cultures. Planta. 215: 1013–1039.
16.Singh, B. and R.P. Rastogi. 1969. A re-investigation of the triterpenes of Centella asiatica. Phytochemistry 8:917–921.
17.Sumaryono, W., P. Proksch, T. Hartmann, M. Nimtz, and V. Wray. 1991. Induction of rosmarinic acid accumulation in cell suspension cultures of Orthosiphon aristatus after treatment with yeast extract. Phytochemistry 30:3267–3271.
18.Suzuki, T., H. Mori, T. Yamame, and S. Shimuzu. 1985. Automatic supplementation of minerals in fed-batch culture to high cell mass concentration. Biotech. Bioeng. 27:192–201.
19.Yan, Q., Z.D. Hu, and J.Y. Wu. 2006. Synergistic effects of biotic and abiotic elicitors on the production of tanshinones in Salvia miltiorrhiza hairy root culture. China. J. Chin. Mater. Med. 31:188–191.
20.Zhang, C., Q. Yan, W.K. Cheuk, and J. Wu. 2004. Enhancement of tanshinone production in Salvia miltiorrhiza hairy root culture by Ag+ elicitation and nutrient feeding. Planta Med. 70:147–151.
21.Zhao, J., L.C. Davis, and R. Verpoorte. 2005. Elicitor signal transduction leading to production of plant secondary metabolites. Biotechnol. Adv. 23:283–333.