1. 金银花提取物honeysuckle flower extract

金银花提取物绿原酸

品名: 金银花提取物绿原酸

拉丁名: Lonicera japonica.

提取部位: 花

外观: 棕色精细粉末

有效成分: 绿原酸

规格: 10:1(TLC),  绿原酸 20%-98%

 金银花提取物是一种提取物，提取自天然植物金银花，主要成份为绿原酸，颜色是棕色粉末，可做为药品、保健品、化妆品的原料。

金银花及金银花提取物的功效：

一是抗菌及抗病毒。即对金黄色葡萄球菌、溶血性链球菌、痢疾、伤寒、脑膜炎双球菌、肺炎双球菌、绿脓以及流感病毒等都有明显抑制作用。

二是有增强免疫的功能。金银花能促进淋巴细胞转化，增强白细胞的吞噬功能。

三是抗炎、解热。金银花能促进肾上腺皮质激素的释放，对炎症有明显抑制作用。

金银花饮片大致可分为生药、炒药、炭药3种。这3种制品的性味和功效有差别，在应用上也各有擅长。生药是把鲜品金银花经过日晒、阴干或烘烤等方法而获得的干品，也指鲜品金银花。生药味甘微苦，性寒，善清解上焦和肌表之毒邪。可用于温病初期，常与连翘、薄荷、淡豆豉、荆芥等同用，以加强疏散清热之力。主要用于温病初起发热，微恶风寒，口微渴者，代表方如“银翘散”。还可用于痈疽疔毒，金银花自古有“疡科之圣药”之称。常与蒲公英、紫花地丁、野菊花等合用，能增强解毒消肿作用。对于痈疽疖毒，红肿疼痛，无论溃脓还是未溃脓者，使用金银花（用量宜重）均能起到 效果。代表方有“五味消毒饮”等。

金银花提取物规格：绿原酸3-98%

以上资料由上禾生物整理

仅供参考

参考文献：

  1. 1.Arbos KA, Claro ML, Borges L, Santos CAM, Weffort-Santos AM (2008) Human erythrocyte as a system for evaluating the antioxidant capacity of vegetable extracts. Nutr Res 28:457–463

  2. 2.Arora A, Byren TM, Nair MG, Strasburg GM (2000) Modulation of liposomal membrane fluidity by flavonoids and isoflavonoids. Arch Biochem Biophys 373(1):102–109 

  3. 3.Attar M, Kates M, Khalil MB, Carrier D, Wong PTT (2000) A Fourier-transform infrared study of the interaction between germ-cell specific sulfogalactosylglycerolipid and dimyristoylglycerophosphocholine. Chem Phys Lipids 106:101–114

  4. 4.Bessis M (1977) La forme et la deformabilite des erythrocytes normaux et dans certaines anemies hemolytiques congenitales. Nouv Rev Fr d’Hematol 18:75–94

  5. 5.Bonarska-Kujawa D, Pruchnik H, Oszmiański J, Sarapuk J, Kleszczyńska H (2011a) Changes caused by fruit extracts in the lipid phase of biological and model membranes. Food Biophys 6:58–67

  6. 6.Bonarska-Kujawa D, Cyboran S, Oszmiański J, Kleszczyńska H (2011b) Extracts from apple leaves and fruits as effective antioxidants. J Med Plants Res 5(11):2339–2347 

  7. 7.Bonarska-Kujawa D, Pruchnik H, Kleszczyńska H (2012) Interaction of selected anthocyanins with erythrocytes and liposome membranes. Cell Mol Biol Lett 17:289–308

  8. 8.Bonarska-Kujawa D, Cyboran S, Żyłka R, Oszmiański J, Kleszczyńska H (2014) Biological activity of blackcurrant extracts (Ribes nigrum L.) in relation to erythrocyte membranes. BioMed Res Int 783059:13.

  9. 9.Bors M, Sicińska P, Michałowicz J, Wieteska P, Gulewicz K, Bukowska B (2012) Evaluation of the effect of Uncaria tomentosa extracts on the size and shape of human erythrocytes (in vivo). Environ Toxic Pharm 33:127–134 

  10. 10.Bradford M (1976) Rapid and sensitive method for the quantization of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254 

  11. 11.Chaudhuri S, Banerjee A, Basu K, Sengupta B, Sengupta PK (2007) Interaction of flavonoids with red blood cell membrane lipids and proteins: antioxidant and antihemolytic effects. Int J Biol Macromol 41:42–48 

  12. 12.Chen PN, Chu SC, Chiou HL, Kuo WH, Chiang CL, Hsieh YS (2006) Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion on human lung cancer cell line. Canc Lett 235:248–259 

  13. 13.Cyboran S, Bonarska-Kujawa D, Kapusta I, Oszmiański J, Kleszczyńska H (2011) Antioxidant potentials of polyphenolic extracts from leaves of trees and fruit bushes. Curr Top Biophys 34:15–21 

  14. 14.Cyboran S, Oszmiański J, Kleszczyńska H (2012) Interaction between plant polyphenols and the erythrocyte membrane. Cell Mol Biol Lett 17:77–88 

  15. 15.Deuticke B (1968) Transformation and restoration of biconcave shape of human erythrocytes induced by amphiphilic agents and changes of ionic environment. Biochim Biophys Acta 163:494–500 

  16. 16.Dodge JT, Mitchell C, Hanahan DJ (1963) The preparation and chemical characteristics of hemoglobin-free ghosts of erythrocytes. Arch Biochem 100:119–130 

  17. 17.Everitt CH, Haydon DA (1968) Electrical capacitance of a lipid membrane separating two aqueous phases. J Theor Biol 18:371–379 

  18. 18.Fettiplace R, Gordon LGM, Hladky SB, Requena J, Zingsheim HP, Hydon DA (1975) Techniques in the formation and examination of “black” lipid bilayer membranes. In: Korn ED (ed) Methods in membrane biology, vol 4. Plenum Press, New York, pp 1–75 

  19. 19.Iglic A, Kralj-Ilgic V, Hagerstand VH (1998) Amphiphile induced echinocyte-spheroechinocyte transformation of red blood cell shape. Eur Biophys J 27:335–339 

  20. 20.Kalinowski S, Figaszewski Z (1995) A four electrode potentiostat-galvanostat for measurements of bilayer lipid membrane capacitance. Meas Sci Technol 6:1043–1049 

  21. 21.Kong JM, Chia LS, Goh NK, Chia TF, Brouillard R (2003) Analysis and biological activities of anthocyanins. Phytochem 64:923–933 

  22. 22.Kusznierewicz B, Piekarska A, Mrugalska B, Konieczka P, Namieśnik J, Bartoszek A (2012) Phenolic composition and antioxidant properties of Polish blue-berried honeysuckle genotypes by HPLC-DAD-MS, HPLC postcolumn derivatization with ABTS or FC, and TLC with DPPH visualization. J Agri Food Chem 60:1755–1763 

  23. 23.Lakowicz JR (2006) Fluorescence anisotropy. Principles of fluorescence spectroscopy, 3rd edn. Springer, New York, pp 353–382 

  24. 24.Lewis RNAH, McElhaney RN, Pohle W, Mantsch HH (1994) Components of the carbonyl stretching band in the infrared spectra of hydrated 1,2-diacylglycerolipid bilayers: a reevaluation. Biophys J 67:2367–2375

  25. 25.Lifen H, Zhou B, Yang L, Liu ZL (2004) Inhibition of free radical initiated peroxidation of human erythrocyte ghosts by flavanols and their glycosides. Org Biomol Chem 2:1419–1423

  26. 26.Maddy AH, Dunn MJ, Kelly PG (1972) The characterization of membrane proteins by centrifugation and gel electrophoresis. A comparison of proteins prepared by different methods. Biochim Biophys Acta 288:263–278

  27. 27.Movileanu L, Neagoe I, Flonta ML (2000) Interaction of the antioxidant flavonoid quercetin with planar lipid bilayers. Int J Pharm 205:135–146

  28. 28.Mueller P, Rudin DO, Tien HT, Wescott WC (1962) Reconstitution of cell membrane structure in vitro and its transformation into an excitable system. Nature 194:979–980

  29. 29.Nenadis N, Boyle S, Bakalbassis EG, Tsimidou M (2003) An experimental approach to structure-activity relationships of caffeic and dihydrocaffeic acids and related monophenols. J Am Oil Chem Soc 80(5):451–458

  30. 30.Oszmiański J, Wojdyło A, Gorzelny J, Kapusta I (2011) Identification and characterization of low molecular weight polyphenols in berry leaf extracts by HPLC-DAD and LC-ESI/MS. J Agri Food Chem 59:12830–12835

  31. 31.Parasassi T, Krasnowska EK, Bagatolli L, Gratton E (1998) Laurdan and prodan as polarity-sensitive fluorescent membrane probes. J Fluorescence 8(4):365–373

  32. 32.Pawlikowska-Pawlęga B, Gruszecki WI, Misiak LE, Gawron A (2003) The study of the quercetin action on human erythrocyte membranes. Biochem Pharmacol 66:605–612

  33. 33.Pawlikowska-Pawlęga B, Misiak LE, Zarzycka B, Paduch R, Gawron A, Gruszecki WI (2013) FTIR, 1H NMR and EPR spectroscopy studies on the interaction of flavone apigenin with dipalmitoylphosphatidylcholine liposomes. Biochem Biophys Acta 1828:518–527

  34. 34.Rice-Evans CA, Miller NJ, Paganga G (1997) Antioxidant properties of phenolic compounds. Trends Plant Sci 2(4):152–159

  35. 35.Rop O, Reznicek V, Mlcek T, Jurikowa T, Balik J, Sochor J, Kramrova D (2011) Antioxidant and radical oxygen species scavenging activities of 12 cultivars of blue honeysuckle fruit. Hort Sci (Prague) 38:63–70

  36. 36.Sheetz MP, Singer SJ (1974) Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions. Proc Nat Acad Sci USA 71:4457–446

  37. 37.Suwalsky M, Oyarce K, Avello M, Villena F, Sotomayor CP (2009) Human erythrocytes and molecular models of cell membranes are affected in vitro by Balbisia peduncularis (Amancay) extracts. Chem-Biol Interact 179:413–418

  38. 38.Tien HT (1974) Bilayer lipid membranes: theory and practice. Marcel Dekker, Inc., New York

  39. 39.Włoch A, Kapusta I, Bielecki K, Oszmiański J, Kleszczyńska H (2013) Activity of hawthorn leaf and bark extracts in relation to biological membrane. J Membr Biol 246:545–556

  40. 40.Xiaofei S, Hu P, Maoxing L, Xiaolou M, Hong D (2011) Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. J Ethnopharm 138:1–21

  41. 41.Zhang YL, Frangos JA, Chachisvilis M (2006) Laurdan fluorescence senses mechanical strain in the lipid bilayer membrane. Biochem Biophys Res Com 347:838–841

  42. 42.Zhinan X, Zhengxiang N (2008) Scavenging and antioxidant properties of compound derived from chlorogenic acid in South-China honeysuckle. LWT 41:1189–1203

回到顶部
桌面版