博落回提取物白屈菜红碱

品名:Macleaya cordata Extrat

拉丁名: Macleaya cordata (Willd.)R.Br.

有效成份:Total alkaloids,sanguinarine,chelerythrine.

外观:orange red  fine powder

规格:Total alkaloids: 20%-60%;

         Ratio product: 5:1, 10:1,20:1 TLC

          sanguinarine 1-30%,chelerythrine:1-50%

检测方式:HPLC / TLC

博落回及博落回提取物在兽药中应用

兽用博落回清热解毒消肿、抗菌抗病毒消炎效果好,是一种 绿色兽药产品。具有清热解毒消肿、抗菌抗病毒消炎功效,用于治疗各种家畜流行性感冒、上呼吸道感染、肺炎、猪肺疫、消化道感染、传染性胃肠炎、腹泻痢疾、仔猪白痢、黄痢、高热性疾病、病毒感染、禽霍乱、鸡白痢等。

饲料添加剂-促生长作用

博落回提取物的主要成分血根碱具有抑制胆碱脂酶活性,刺激唾液分泌,并具有利尿、外周抗肾上腺素解交感作用(Federico Bianco等,2006)。博落回及博落回提取物在兽药中应用 同时具有能抑制芳香族氨基酸脱羧酶的作用,Drata等(1996)认为,血根碱通过这一作用调节色氨酸-5-羟色胺代谢途径,而增加饲养动物的采食量。而Lenfeld等(1981)研究认为,博落回中含有的QBA的这两种作用的结合是它提高动物生长性能的原因。QBA可能通过与肠道接触而发挥抗菌和抗炎的作用,从而降低断奶仔猪腹泻率、保障肠道健康,可能是提高动物生产性能的主要原因。

血根碱系为中华人民共和国农业部公告第318号中公布的饲料添加剂品种。

博落回提取物总碱1-60%

以上资料 由长沙上禾生物整理  产品详询13657416805

References参考文献:

  1. 1. 

    Lilley DMJ (1995) Proc Natl Acad Sci USA 92:7140–7142 

  2. 2. 

    Hermann T, Patel DJ (2000) Structure 8:R47–R54 

  3. 3. 

    Xi Z, Hwang GS, Goldberg IH, Harris JL, Pennington WT, Fouad FS, Qabaja G, Wright JM, Jones GB (2002) Chem Biol 9:925–931

  4. 4. 

    Nakatani K, Horie S, Murase T, Hagihara S, Saito I (2003) Bioorg Med Chem 11:2347–2353 

  5. 5. 

    Nakatani K, Sando S, Saito I (2000) J Am Chem Soc 122:2172–2177

  6. 6. 

    Xi Z, Goldberg IH (2002) Enediyne antibiotic neocarzinostatin as a radical-based probe of bulged structures in nucleic acids. In: Jones GB, Chapman BJ (eds) Advances in DNA sequence-specific agents. Elsevier, Amsterdam, Netherlands

  7. 7. 

    Malkov VA, Biswas I, Camerini-Otero D, Hsieh P (1997) J Biol Chem 272:23811–23817

  8. 8. 

    Wang YH, Bortner CD, Griffith J (1993) J Biol Chem 268:17571–17577

  9. 9. 

    Lilley DMS (1995) Proc Natl Acad Sci USA 92:7140–7142

  10. 10. 

    Dingwall C, Ernberg I, Gait MJ, Gree SM, Heaphy S, Karn J, Lowe AD, Singh M, Skinner MA, Valerio R (1989) Proc Natl Acad Sci USA 86:6925–6929

  11. 11. 

    Greenblatt J, Nodwell JR, Mason SW (1993) Nature 364:401–406

  12. 12. 

    Wells RD (1996) J Biol Chem 27:2875–2878

  13. 13. 

    Perutz MF (1996) Curr Opin Struct Biol 6:848–858

  14. 14. 

    Kunkel TA (1993) Nature 365:207–209

  15. 15. 

    Harvey SC (1997) Biochemistry 36:3047–3049

  16. 16. 

    Kappen LS, Xi Z, Jones GB, Goldberg IH (2003) Biochemistry 42:2166–2173

  17. 17. 

    Ashley CT, Warren ST (1995) Annu Rev Genetics 29:703–728

  18. 18. 

    Adhami VM, Aziz MH, Reagan-Shaw SR (2004) Mol Cancer Ther 3:933–940

  19. 19. 

    Ahmad N, Gupta S, Husain MM, Heiskanen KM, Mukhtar H (2000) Clin Cancer Res 6:1524–1528

  20.  

    20. 

    Chmura SJ, Dolan ME, Cha A, Mauceri HJ, Kufe DW, Ralph R (2000) Clin Cancer Res 6:737–742

     

  21. 21. 

    Bai LP, Zhao ZZ, Cai Z, Jiang ZH (2006) Bioorg Med Chem 14:5439–544 

  22. 22. 

    Xi Z, Zhang R, Yu Z, Ouyang D, Huang R (2005) Bioorg Med Chem Lett 15:2673–2677 

  23. 23. 

    Bai LP, Zhao ZZ, Cai Z, Jiang ZH (2006) Nucleic Acids Symp Ser 50:197–198

  24. 24. 

    Schneider HJ, Yatsimirsky AK (2000) Principles and methods in supramolecular chemistry. Wiley, New York

  25. 25. 

    Wan KX, Shibue T, Gross M (2000) J Am Chem Soc 122:300–307

  26. 26. 

    Chen WH, Chan CL, Cai Z, Luo GA, Jiang ZH (2004) Bioorg Med Chem Lett 14:4955–4959

  27. 27. 

    Moody EM, Bevilacqua PC (2004) J Am Chem Soc 126:9570–9577

  28. 28. 

    Qin Y, Pang JY, Chen WH, Cai Z, Jiang ZH (2006) Bioorg Med Chem 14:25–32

  29. 29. 

    Long YH, Bai LP, Qin Y, Pang JY, Chen WH, Cai Z, Xu ZL, Jiang ZH (2006) Bioorg Med Chem 14:4670–4676

  30. 30. 

    Senior MM, Jones RA, Breslauer KJ (1988) Proc Natl Acad Sci USA 85:6242–6246

  31. 31. 

    Rosu F, Pirotte S, De Pauw E, Gabelica V (2006) Int J Mass Spectrum 253:156–171

  32. 32. 

    Carrasco C, Rosu F, Gabelica V, Houssier C, De Pauw E, Garbay-Jaureguiberry C, Roques B, Wilson WD, Chaires JB, Waring MJ, Bailly C (2002) ChemBioChem 3:1235–1241

  33. 33. 

    Rosu F, De Pauw E, Guittat L, Alberti P, Lacroix L, Mailliet P, Riou JF, Mergny JL (2003) Biochemistry 42:10361–10371

  34. 34. 

    Jones GB, Lin Y, Xiao Z, Kappen L, Goldberg IH (2007) Bioorg Med Chem 15:784–790

  35. 35. 

    Xi Z, Zhang R, Yu Z, Ouyang D (2006) Bioorg Med Chem Lett 16:4300–4304