English name:Magnolol
Molecular formula and molecular weight:C18H18O2, 266.32
CAS number:528-43-8
Specification:1-98%
Test method:HPLC
厚朴药用价值很高,其树皮,根皮,花,果,均可入药。厚朴不同部位药用成分不同,其中以厚朴树皮,根皮中的厚朴酚与和厚朴酚为主,不同树龄的厚朴皮中的成分基本相同,但药用含量不同。由于厚朴树皮总酚含量较低,一般在2%-6%之间,而且随产地不同原料总酚含量差异较大, 而16年以上根皮总酚平均都能达到10%以上,因此综合考虑,我们选用20年以上,产地湖北西部,湖南西南部的根皮生产厚朴酚与和厚朴酚。
厚朴的主要成分:木脂体类化合物:厚朴酚(magnolol),和厚朴酚(honokiol),和厚朴新酚(obovatol),6’-O-甲基和厚朴酚(6’-O-methylhonokiol)等。
生物碱:木兰箭毒碱(magnocurarine)和柳叶木兰碱(salicifoline);
挥发油:含30多种成分,主要的有β-桉叶醇(β-eudesmol)17.4%,荜澄茄醇(cadinol)14.6%,愈创萜醇(guaiol)8.7%等。
另还含芥子醛(sin ldehyde),丁香树脂酚(syringaresinol),丁香树脂酚-4’-O-β-D-吡喃葡萄糖甙等。
厚朴提取物的主要成分是厚朴酚、和厚朴酚,厚朴油挥发油的主要成分为桉叶油醇,厚朴提取物中的生物碱有厚朴碱,在一定的贮藏年限内,厚朴贮藏有利于酚类含量的转化与积累
日化洗护应用
1、用于口香糖、牙膏、漱口水产品,预防牙斑和牙龈炎,防龋齿,防口臭;
2、用于洗发水,可止屑去痒,健康毛囊
3、用于沐浴露,可抗菌、美白、止痒
化妆品方面应用
1、和厚朴酚的抗菌性可用作化妆品防腐剂
2、美白淡斑的水、乳、膏、霜、面膜
3、祛痘消炎的膏、霜、面膜
产品详询:13657416805
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35.Role of magnolol in the proliferation of vascular smooth muscle cells
Proliferation of vascular smooth muscle cells (VSMCs) contributes to the development of vascular remodeling. Recently, magnolol has been reported to have a potential ... proliferation of VSMCs. However, the role ...
L. Wu, H. Zou, W. Xia, Q. Dong, L. Wang in Herz (2015)
36.Interaction of magnolol with bovine serum albumin: a fluorescence-quenching study
The interaction of magnolol with bovine serum albumin(BSA) was studied... K, and the ratio of quantum yields of protein fluorescence for complex and free protein, f, at 298 K, 304 K, and 310 K were obtained; the ...
Jiaqin Liu, Jian-niao Tian, Jiyou Zhang, Zhide Hu… in Analytical and Bioanalytical Chemistry (2003)
37.Electrochemical behavior of magnolol on FeWO4 nanoflower modified carbon paste electrode
In order to establish a simple, sensitive, and fast reliable detection method to determine the magnolol, FeWO4 nanoflower was synthesised through a solvothermal technique and FeWO4...nanoflower modified carbon pa...
Weibing Hu 胡卫兵, Wen Zhang, Nannan Song… in Journal of Wuhan University of Technology-… (2016)
38.Sensitive and selective electrochemical sensor for magnolol based on the enhancement effect of multiwalled carbon nanotubes
Herein, insoluble multiwalled carbon nanotubes (MWNTs) were dispersed into N,N...-dimethylformamide (DMF) via ultrasonication, resulting in a stable and homogeneous MWNTs suspension. After evaporation of DMF, the...
Wensheng Huang, Tian Gan, Shijia Luo, Shenghui Zhang in Ionics (2013)
39.Mesoporous silica-based electrochemical sensor for simultaneous determination of honokiol and magnolol
A kind of mesoporous SiO2 was synthesized using cationic surfactant as the structure-directing template. After that, the resulting mesoporous SiO2...was used to modify the carbon paste electrode (CPE). The electr...
Jun Zhao, Wensheng Huang, Xiaojiang Zheng in Journal of Applied Electrochemistry (2009)
40.Inhibitory Effects of Honokiol and Magnolol on Biofilm Formation by Acinetobacter baumannii
Acinetobacter baumannii...is a nosocomial pathogen that can survive unfavorable conditions, such as, desiccation, nutrient starvation, and antimicrobial treatment, and this is primarily due to its ability to form...
Sagar Kiran Khadke, Jin-Hyung Lee, Je-Tae Woo… in Biotechnology and Bioprocess Engineering (2019)
41.Effect of magnolol on cerebral injury and blood brain barrier dysfunction induced by ischemia-reperfusion in vivo and in vitro
Magnolol, a neolignan compound isolated from traditional Chinese...Magnolia officinalis..., has a potentially therapeutic influence on ischemic stroke. Previous studies have demonstrated that cerebral ischemia-re...
Xiaoyan Liu, Xiaoling Chen, Yuanjun Zhu, Kewei Wang, Yinye Wang in Metabolic Brain Disease (2017)
42.Synergistic effect of lysozyme on bactericidal activity of magnolol and honokiol against a cariogenic bacterium,Streptococcus mutans OMZ 176
A combination of magnolol or honokiol with lysozyme isolated from the...Streptococcus mutans OMZ 176. The synergistic ratio increased with time dependence.
Kihwan Bae, Hongrock Oh in Archives of Pharmacal Research (1990)
43.The absorption and transport of magnolol in Caco-2 cell model
To investigate the absorption and transport mechanism of magnolol in Caco-2 cell model.
An-guo Wu 吴安国, Bao Zeng 曾 宝, Meng-qiu Huang 黄孟秋… in Chinese Journal of Integrative Medicine (2013)
44.Separation and determination of magnolol and honokiol inMagnolia officinalis bark by capillary zone electrophoresis
The effects of pH on separation parameters such as migration mobility, resolution, sensitivity, column efficiency and peak shape were emphatically studied. Better separation of magnolol and honokiol using capilla...
Ziping Zhang, Zhide Hu, Gengliang Yang in Microchimica Acta (1997)
45.Preparation and Property Analysis of Natural Antibacterial Agents-Magnolol and Chitosan-Based Antibacterial Wrapping Paper
In this paper, chitosan and magnolol and their compound were used as antibacterial ... to compare the antibacterial effects of chitosan and magnolol, The preservation effect of antibacterial wrapping paper ... re...
Yan Zhang, Deshui Li, Qingbao Wei in Advanced Graphic Communication, Printing a… (2020)
46.Anti-inflammatory and analgesic effects of magnolol
Magnolol, isolated from Magnolia officinalis..., inhibited mouse hind-paw edema induced by carrageenan, compound 4880, polymyxin B and reversed passive Arthus reaction. Acetic acid-induced writhing response was d...
Jih-Pyang Wang, Mei-Feng Hsu… in Naunyn-Schmiedeberg's Archives of Pharmaco… (1992)
47.Synthesis of 1-[3-(N-pyrrole)propyl]-3-[1-tert-butoxycarbonylamino-propyl]-imidazolium tetrafluoroborate ionic liquid for application in electrochemical sensing of magnolol
...1-[3-(N-Pyrrole)propyl]-3-[1-tert-butoxy-carbonylamino-propyl]imidazolium tetrafluoroborate ionic liquid was successfully synthesized and characterized. The ionic liquid was electrochemically polymerized onto ...
Guishen Liu, Yanhui Ma, Xiaodong Hou, Yina huang, Jianpeng Chen, Guoqing Zhan… in Ionics (2015)
48.Mechanistic Evidence to Support the Anti-hepatitis B Viral Activity of Multifunctional Scaffold & Conformationally Restricted Magnolol
Magnolol, phenolic bioactive phytomolecule, is a potential ... mechanistically analyze the probable site of action for magnolol. Magnolol has been docked with EF3-CaM adenylyl ... and clinical development of semi...
Rajeev K. Singla in National Academy Science Letters (2014)
49.High-Performance Thin-Layer Chromatographic-Bioautographic Method for the Simultaneous Determination of Magnolol and Honokiol in Magnoliae officinalis Cortex
A simple and accurate high-performance thin-layer chromatography (HPTLC)-bioautographic method was developed for the quantitative analysis of magnolol and honokiol in the herbal medicine Magnoliae officinalis Cor...
Lihua Gu, Shansong Zheng, Tao Wu… in JPC – Journal of Planar Chromatography – M… (2014)
50.Self-assembly and hydrothermal technique syntheized Fe2O3-RGO nanocomposite: The enhancement effect of electrochemical simultaneous detection of honokiol and magnolol
The nanocomposite of Fe2O3-reduced graphene oxide (Fe2O3-RGO) was synthesized by a hydrothermal reduction using self-assembly of Fe(OH)3...colloidal suspension and graphene oxide (GO) as precursors at 180°C. The ...
Weibing Hu, Wen Zhang, Yan Wu, Wanyun Qu in Journal of Electroceramics (2018)
51.Separation and determination of honokiol and magnolol in herbal medicines by flow injection-capillary electrophoresis
A simple, rapid, and accurate method for the separation and determination of honokiol and magnolol in Magnolia officinalis and related herbal medicines was developed by combination of flow injection (FI) and capi...
Lihong Liu, Xinan Wu, Liuyin Fan, Xingguo Chen… in Analytical and Bioanalytical Chemistry (2006)
52.Honokiol and Magnolol Inhibit CXCL10 and CXCL11 Production in IL-27-Stimulated Human Oral Epithelial Cells
Honokiol and magnolol, which are lignans isolated from Magnolia quinquepeta ... , the anti-inflammatory effects of honokiol and magnolol on periodontal disease are still uncertain. The ... was to examine the effe...
Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo in Inflammation (2018)
53.Protective Effect of Magnolol on Lipopolysaccharide-Induced Acute Lung Injury in Mice
Magnolol, a tradition Chinese herb, displays an ... effects. To investigate the protective effect of magnolol on lipopolysaccharide (LPS)-induced acute lung ... kg). The mice received intratracheal instillation o...
Yun Feng Ni, Tao Jiang, Qing Shu Cheng, Zhong Ping Gu, Yi Fang Zhu… in Inflammation (2012)
54.Antifungal activity of magnolol and honokiol
Two neolignan compounds, magnolol (5,5′-diallyl-2,2′-dihydroxybiphenyl...1) and honokiol (5,5′-diallyl-2,4′-dihydroxybiphenyl,2), were isolated from the stem bark ofMagnolia obovata and evaluated for antifungal a...
Kyu Ho Bang, Yoon Kwan Kim, Byung Sun Min, Min Kyun Na… in Archives of Pharmacal Research (2000)