1. Ferulic acid

Ferulic acid 98%

Product  Name: Ferulic acid

Part Used:Rice bran

Appearance:White powder

CAS No.:135-24-6

Molecular formula: C10H10O4

Molucular weight: 194.18

Test Method:HPLC

 

About Ferulic acid:

Ferulic acid, like many natural phenols, is an antioxidant in vitro in the sense that it is reactive toward free radicals such as reactive oxygen species (ROS). ROS and free radicals are implicated in DNA damage, cancer, accelerated cell aging. Animal studies and in vitro studies suggest that ferulic acid may have direct antitumor activity against breast cancer and liver cancer. Ferulic acid may have pro-apoptotic effects in cancer cells, thereby leading to their destruction. Ferulic acid may be effective at preventing cancer induced by exposure to the carcinogenic compounds benzopyrene and 4-nitroquinoline 1-oxide.Note that these are not randomized controlled trials done with human participants, and therefore, the results of these studies may not be directly applicable to human use.

 

If added to a topical preparation of ascorbic acid and vitamin E, ferulic acid may reduce oxidative stress and formation of thymine dimers in skin.There is also a small amount of research showing oral supplements of ferulic acid can inhibit melanin production in the process of skin whitening.

 

Staherb Ferulic acid Main Function:

1.Enhance human bodys motility of sperm and mobility;
2.Inhibiting platelet aggregation, increase 3H-5HT releasing from platelet;
3.Antioxidation, clear free radical, protective cell, accommodate body immune function;
4.Anti-bacteria, anti-inflammatory, anti-tumor, anti- mutation, anti- ultraviolet radiation;
5.Inhibit thrombosis, lower blood viscosity, in order to increase brain microcirculation, it can used for curing ischemia palsy.

 

Staherb Ferulic acid Application:

Ferulic acid is wide used into medicine, food, cosmetics field . It was used as the anti-inflammatory Drugs, pain, antithrombotic, ultraviolet radiation, anti-free radical and immune function of human body ,In the clinical ,it was used as the treatment of those diseases such as coronary heart disease, cerebrovascular disease, vasculitis, leukopenia and thrombocytopenia. It also wide used in the food, cosmetic, mainly as an antioxidant .

 

ANALYSIS

SPECIFICATION 

Appearance

White to off-white powder

Odor

Characteristic

Assay(Ferulic acid,HPLC)

≥99%

Loss on Drying

≤0.5%

Heavy Metal

<10ppm

 

 

Microbiology

 

Total Plate Count

<1000cfu/g

Yeast & Mold

<100cfu/g

E.Coli

Negative

Salmonella

Negative

 

For more product information for ferulic aicd,Pls contact me at email sales09@staherb.cn 

 

References

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  4. 4.Borneman WS, Ljungdahl LG, Hartley RD, Akin DE (1992) Purification and partial characterisation of two feruloyl esterases from the anaerobic fungus Neocalimastix strain MC-2. Appl Environ Microbiol 58:3762–3766

  5. 5.Castanares A, McCrea SI, Wood TM (1992) Purification and properties of a feruloyl/p-coumaroyl esterase from the fungus Penicillium pinophilum. Enzyme Microb Technol 14:875–884

  6. 6.Colquhoun IJ, Ralet MC, Thibault JF, Faulds CB, Williamson G (1994) Structure identification of feruloylated oligosaccharides from sugar-beet pulp by NMR spectroscopy. Carbohydr Res 263:243–256

  7. 7.Faulds CB, Williamson G (1991) The purification and characterisation of 4-hydroxy-3-methoxycinnamic (ferulic) acid esterase from Streptomyces olivochromogenes. J Gen Microbiol 137:2339–2345.

  8. 8.Faulds CB, Williamson G (1993a) Release of ferulic acid from plant polysaccharides by ferulic acid esterase from Streptomyces olivochromogenes. Carbohydr Polymers 21:153–155

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  10. 10.Faulds CB, Williamson G (1994) Purification and characterisation of a ferulic acid esterase (FAE-III) from Aspergillus niger:specificity for the phenolic moiety and binding to microcrystalline cellulose. Microbiology 140:779–787

  11. 11.Faulds CB, Ralet MC, Williamson G, Hazlewood GP, Gilbert HJ (1995) Specificity of an esterase (XYLD) from Pseudomonas fluorescens subsp. cellulosa. Biochim Biophys Acta 1243:265–269

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  18. 18.Kellet LE, Poole DM, Ferreira LMA, Durrant AJ, Hazlewood GP, Gilbert HJ (1990) Xylanase B and an arabinofuranosidase from Pseudomonas fluorescens subsp. cellulosa contains identical cellulose-binding domains and are encoded by adjacent genes. Biochem J 272:369–376

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  22. 22.Poutanen K (1988) Characterisation of xylonolytic enzymes for potential applications. Publication 47, Technical Research Centre of Finland, Espoo.

  23. 23.Puls J, Poutanen K. (1989) Mechanisms of enzymatic hydrolysis of hemicelluloses (xylans) and procedures for determination of the enzyme activities involved. In Coughlan MP (ed) Enzyme systems for lignocellulose degradation. Elsevier, Amsterdam. pp 151–165

  24. 24.Ralet M.C, Thibault JF, Faulds CB, Williamson G (1994a) Isolation and purification of feruloylated oligosaccharides from cell-walls of sugar-beet pulp. Carbohydr Res 263:227–241

  25. 25.Ralet MC, Faulds CB, Williamson G, Thibault JF (1994b) Degradation of feruloylated oligosaccharides from sugar-beet pulp and wheat bran by ferulic acid esterases from Aspergillus niger. Carbohydr Res 263:257–269

  26. 26.Rombouts FM, Thibault JF (1986) Feruloylated pectic substances from sugar beet pulp. Carbohydr Res 154:177–187

     

  27. 27.Royer JC, Nakas JP (1991) Purification and characterisation of two xylanases from Trichoderma longibrachiatum. Eur J Biochem 202:521–529 

  28. 28.Smith MM, Hartley RD (1983) Occurrence and nature of ferulic acid substitution of cell-wall polysaccharides in graminaceous plants. Carbohydr Res 118:65–80

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