Rosemary leaf extract ursolic acid

Product Name:rosemary extract ursolic acid

Appearance:brown powder to white color

Active Ingredient:ursolic acid

Plant Origin:Rosmarinus officinalis L

CAS No.:80225-53-2 

Molecular Formula:C18H16O8

Molecular Weight:360.33


Test Method:HPLC

About Rosemary leaf extract

Rosmarinus officinalis, commonly known as rosemary, is a woody, perennial herb with fragrant, evergreen, needle-like leaves and white, pink, purple, or blue flowers, native to the Mediterranean region,which active ingredients including ursolic acid,rosmarinic acid,carnosic acid.


Ursolic acid

Ursolic acid, also known as urson, prunol and malol is a pentacyclic triterpenoid compound which is naturally presented in a large number of vegetarian foods, medicinal herbs, and other plants. We extract the Ursolic acid from leaf of Rosemary(Rosmarinus officinalis Linn.) 

Research indicates that the ursolic acid has a decent effect on anti-aging,anti-freckle by its anti-oxidant activity. It can prevent the appearance of wrinkles and age spots by restoring the skin's collagen bundle structures and its elasticity. As a cosmetic agent,it is stable,the color and odor of which will not be changing easily over time, and has a good sense of touching. Thus it has been widely used in the health food, pharmaceutical and cosmetic fields as the raw materials.


Rosemary Extract




Test Method



Rosmarinic acid




Brown yellow to yellow powder

   Water        soluble

Carnosic acid



Brown yellow to yellow  powder

Oil soluble

Carnosic acid




Brown yellow liquid

Ursolic acid



Greenish yellow to white

     Water          soluble


essential oil



Light yellow liquid








 Rosemary extract ursolic acid Application:

1. Applied in food field.

2. Applied in health product field 

3. Applied in cosmetics field.


Rosemary extract ursolic acid Usage:

1. Reduce the skin congestion, edema, swelling; 
2. Good for gastrointestinal, heart, lungs, liver, gallbladder; 
3. Convergence skin, improve dandruff; Relief menorrhalgia, diuresis, weight loss                                            
4. Cardiac stimulant, fall blood pressure, regulate anemia; Refreshing, refreshment, recover central nervous energy. 
5. Using after reducing weight of convergence for skin, it can make the skin more firm and elastic. 

For more product information pls contact email


  1. 1.
    Wu JW, Lee M-H, Ho C-T, Chang SS (1982) Elucidation of the chemical structures of natural antioxidants from rosemary. J Am Oil Chem Soc 59:339–345
  2. 2.
    Fischer C (1992) Phenolic compounds in spices. In: Ho C-T, Lee CY, Huang M-T (eds) Phenolic compounds in food and their effects on health I: Analysis, occurrence, and chemistry, chapt 9, The American Society Symposium series 546, Washington DC, pp 118–129
  3. 3.
    Nakatani N (1992) Natural antioxidants from spices. In: Huang MT, Ho C-T, Lee CY (eds) Phenolic compounds in food and their effects on health II: Antioxidants and cancer prevention, chapt 7, The American Chemical Society Symposium series 546, pp 72–86
  4. 4.
    Nakatani N, Inatani R (1984) Two antioxidative diterpenes from rosemary (Rosmarinus officinalis L.) and a revised structure for rosmanol. Agri Biol Chem 48:2081–2085
  5. 5.
    Ito N, Fukushima S, Hagiwara A, Shibata M, Ogiso T (1983) Carcinogenicity of butylated hydroxyanisole in F344 rats. J Natl Cancer Inst 70:343–352
  6. 6.
    Witschi HR, Morse CC (1983) Enhancement of lung tumor formation in mice by dietary butylated hydroxyltoluene: dose-time relationships and cell kinetics. J Natl Cancer Inst 71:859–865
  7. 7.
    Huang M-T, Ho C-T, Wang ZY, Ferraro T, Lou Y-R, Stauber K, Ma W, Georgiadis C, Laskin JD, Conney AH (1994) Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. Cancer Res 54:701–708
  8. 8.
    Huang M-T, Smart RC, Wong C-Q, Conney AH (1988) Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetra-decanoylphorbol-13-acetate. Cancer Res 48:5941–5946
  9. 9.
    Wattenberg LW (1987) Inhibitory effects of benzyl isothiocyanate administered shortly before dimethylnitrosamine or benzo[a]pyrene on pulmonary and forestomach neoplasia in A/J mice. Carcinogenesis 8:1971–1973
  10. 10.
    Deschner EE, Ruperto J, Wong G, Newmark HL (1991) Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 12:1193–1196
  11. 11.
    Ho C-T, Ferraro T, Chen Q, Rosen RT, Huang M-T (1994) Phytochemicals in teas and rosemary and their cancer-preventive properties. In: Ho CT, Osawa T, Huang M-T, Rosen RT (eds), Food phytochemicals for cancer prevention II: Teas, spices, and herbs. The American Chemical Society Symposium series 547, Washington DC, pp 2–19
  12. 12.
    Singletary KW, Nelshoppen JM (1991) Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and in vivo formation of mammary DMBA-DNA adducts by rosemary extract. Cancer Lett 60:169–175
  13. 13.
    Offord EA, Mace K, Ruffieux C, Malnoe A, Pfeifer, AMA (1995) Rosemary components inhibit benzo[a]pyrene-induced genotoxicity in human bronchial cells. Carcinogenesis 16:2057–2062
  14. 14.
    Hirota H, Mori T, Yoshida M, Iriye R (1990) Suppression of tumor promoter-induced inflammation of mouse ear by ursolic acid and 4,4-dimethylcholestane derivatives. Agr Biol Chem 54:1073–1975
  15. 15.
    Ohigashi H, Takmura H, Koshimizu K, Tokuda H, Ito Y (1986) Search for possible antitumor promoters by inhibition of 12-O-tetradecanoylphorbol-13-acetate Epstein-Barr virus activation; ursolic acid and oleanolic acid from an anti-inflammatory Chinese medicinal plant, Glechoma hederaceae L. Cancer Lett 30:143–151
  16. 16.
    Huang M-T, Ma W, Ho C-T, Lou Y-R, Xie J-G, Conney AH (1995) Inhibitory effect of dietary rosemary on mammary and colon carcinogenesis in mice. Proc Amer Assoc Cancer Res 36:590
  17. 17.
    Tokuda H, Ohigashi H, Koshimizu K, Ito Y (1986) Inhibitory effects of ursolic and oleanolic acid on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Cancer Lett 33:279–285