Neohesperidin dihydrochalcone

1.Name:Neohesperidin dihydrochalcone / NHDC

2.Appearance:White powder

3.Specs.: 98%

4.CAS. 20702-77-6

5.Test method: HPLC

6.Active ingredient: Neohesperidin dihydrochalcone

7. Appearance: White powder


What is Neohesperidin?

  Neohesperidin dihydrochalcone(NHDC), was discovered during the 1960s for minimizing the taste of bitter flavorants in citrus juices. Neohesperidin when treated with potassium hydroxide or another strong base, and then catalytically hydrogenated, it becomes NHDC, a compound roughly 1500-1800 times sweeter than sugar at threshold concentrations; around 340 times sweeter than sugar weight-for-weight. 
Like other highly sweet glycosides, such as glycyrrhizin and those found in stevia, NHDC's sweet taste has a slower onset than sugar's and lingers in the mouth for some time. Unlike aspartame, NHDC is stable to elevated temperatures and to acidic or basic conditions, and so can be used in applications that require a long shelf life. NHDC itself can stay foodsafe for up to five years when stored in optimal conditions.

 NHDC in pure form is found as a white substance not unlike powdered sugar. In food it is used as a flavour enhancer in concentrations of around 4-5 parts per million (ppm) and as an artificial sweetener at around 15-20 ppm.


Citrus aurantium extract




Test Method






Brown-yellow powder

Slightly soluble

in water and





Yellow to light brown powder

Slightly soluble

in methanol




Yellow to dark brown powder

Slightly soluble

in water and





Off-White or light

yellow powder

soluble in hot

water and






Grayish Yellow or

yellow powder

Slightly soluble

in water

Citrus Bioflavonoids



Brown-yellow powder

Slightly soluble

in water




White Crystalline


soluble in hot

water and







Yellow to Brown

Partially soluble in hot water and ethanol





soluble in water





Yellow to Brown 

soluble in water


NHDC main function:

1. Enhance the action of Vitamin C: relief the blood cell coagulation in conjunctiva of guinea pig due to lack of Vitamin C; it is also reported that it can reduce blood cell coagulation in horse. The life span of tats is prolonged when the product is fed with thrombogenic feed or feed that may cause atherosis. Can raise the Vitamin C concentration in adrenal gland, spleen and white blood cell in guinea pig.
2. All capability: when fibrocytes of mice are treated with the product in 200μg/ml solution, the cells can resist the attack from phlyctenular stomatitis virus for 24 hours. Hela cells treated with the product can resist the infection from flu virus. The antiviral activity of the product may be attenuated by hyaluronidase.
3. Other: prevent injury from cold; inhibit aldehyde reductase in lens of rat eyes


NHDC application

1. Applied in food field, it is used as a flavor enhancer and sweetener in a wide variety of Alcoholic beverage, dessert foods and savory foods.
2. Applied in cosmetics, it can added into toothpaste and mouth wash.
3. Applied in pharmaceutical field, it is mainly used to reducing the bitterness of in form.
4. Applied in Feed Field,Used for livestock feed as a means of reducing feeding time.


For more product information pls kindly contact email


Physical index 

Botanical Source:

Citrus Aurantium L

Part used:



NHDC 98%


White fine powder

  Flavor & Odor


  Particle size

100% pass 80 mesh



  Loss on Drying


  Bulk density


  Sulphated Ash




  General Status














  Total microbacterial count


  Yeast & Mold




  Staphylococcus aureus








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