Magnolol


English name:Magnolol
Molecular formula and molecular weight:C18H18O2, 266.32
CAS number:528-43-8

Specification:1-98%

Test method:HPLC



Magnolia is a large genus of about 210 flowering plant species in the subclass Magnolioideae of the family Magnoliaceae. Having evolved before bees appeared, the flowers developed to encourage pollination by beetles. As a result, the carpels of Magnolia flowers are tough, to avoid damage by eating and crawling beetles. Another primitive aspect of Magnolias is their lack of distinct sepals or petals.The bark from M. officinalis has long been used in traditional Chinese medicine, where it is known as hou po . In Japan, koboku, M. obovata has been used in a similar manner. The aromatic bark contains magnolol and honokiol, two polyphenolic compounds that may have demonstrated antianxiety and antiangiogenic properties. Magnolia bark also may have been shown to reduce allergic and asthmatic reactions.

 

Magnolol is an active ingredient of Magnolia officinalis Rehderet Wilson in the skin of Magnolia officinalis Rehderet Wilson. It has a special, long-lasting muscle relaxation effect and a strong antibacterial effect, which can inhibit platelet aggregation. It is mainly used as an antibacterial and antifungal drug in clinical practice.

 

Staherb Magnolol main function:

(1). With the significant effect on muscle pain and in dental care; 
(2). With the significant effect on abdominal distension, diarrhea and other digestive problems and, respiratory problems;
(3).With good function of anti-anxiety;
(4).With the function of antibacterial, it has significant therapeutic efficacy on acute enteritis, bacterial or amoebic dysentery, chronic gastritis and other diseases.

 

Staherb Magnolol Application:

 (1). As the medicine of anti-inflammatory, antibacterial, antioxidant and anti-tumor drug, it is widely used in the fields of medicine and health products;
(2). As a strong antioxidant, it is widely used in cosmetics industry.

 

Why choose STAHERB for Magnolia Bark Extract(magnolol,honokiol,magnolol+honokiol)

 

1. Founded in 2010, Changsha staherb natural ingredients co.,ltd is a professional standardized plant extract manufacturer.

2.Hunan is the origin of Magnolia officinalis. Hunan is the most important production base of Magnolia officinalis in China. It is rich in wild resources. Changsha staherb and the local farmers have built a planting base of Magnolia officinalis with sufficient raw materials. Changsha staherbs  Magnolia production workshop is located in the raw material base, with better quality control of raw materials, lower production cost and better price.

3.Magnolia officinalis extract is the main product of Changsha Staherb, which is produced throughout the year, with stable quality and spot supply.

4.Staherb has a complete set of quality testing equipment and system, quality assurance.

5.The Magnolia officinalis extract of Staherb is produced by supercritical CO2 extraction technology, with large production and good quality control. No organic reagent is used in the extraction process, so the product quality is better and safer

6.Staherb Magnolia extract series products include: Magnolia+honokiol 1-98%, Magnolol 1-98%, and honokiol 1-98%, magnolia oil, magnolia oil extract, etc., full specifications products to meet your need.

 

For more product information pls contact email sales09@staherb.cn

 

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35.Role of magnolol in the proliferation of vascular smooth muscle cells
Proliferation of vascular smooth muscle cells (VSMCs) contributes to the development of vascular remodeling. Recently, magnolol has been reported to have a potential ... proliferation of VSMCs. However, the role ...
L. Wu, H. Zou, W. Xia, Q. Dong, L. Wang in Herz (2015)

36.Interaction of magnolol with bovine serum albumin: a fluorescence-quenching study
The interaction of magnolol with bovine serum albumin(BSA) was studied... K, and the ratio of quantum yields of protein fluorescence for complex and free protein, f, at 298 K, 304 K, and 310 K were obtained; the ...
Jiaqin Liu, Jian-niao Tian, Jiyou Zhang, Zhide Hu… in Analytical and Bioanalytical Chemistry (2003)

37.Electrochemical behavior of magnolol on FeWO4 nanoflower modified carbon paste electrode
In order to establish a simple, sensitive, and fast reliable detection method to determine the magnolol, FeWO4 nanoflower was synthesised through a solvothermal technique and FeWO4...nanoflower modified carbon pa...

Weibing Hu 胡卫兵, Wen Zhang, Nannan Song… in Journal of Wuhan University of Technology-… (2016)

38.Sensitive and selective electrochemical sensor for magnolol based on the enhancement effect of multiwalled carbon nanotubes
Herein, insoluble multiwalled carbon nanotubes (MWNTs) were dispersed into N,N...-dimethylformamide (DMF) via ultrasonication, resulting in a stable and homogeneous MWNTs suspension. After evaporation of DMF, the...

Wensheng Huang, Tian Gan, Shijia Luo, Shenghui Zhang in Ionics (2013)

39.Mesoporous silica-based electrochemical sensor for simultaneous determination of honokiol and magnolol
A kind of mesoporous SiO2 was synthesized using cationic surfactant as the structure-directing template. After that, the resulting mesoporous SiO2...was used to modify the carbon paste electrode (CPE). The electr...

Jun Zhao, Wensheng Huang, Xiaojiang Zheng in Journal of Applied Electrochemistry (2009)

40.Inhibitory Effects of Honokiol and Magnolol on Biofilm Formation by Acinetobacter baumannii
Acinetobacter baumannii...is a nosocomial pathogen that can survive unfavorable conditions, such as, desiccation, nutrient starvation, and antimicrobial treatment, and this is primarily due to its ability to form...

Sagar Kiran Khadke, Jin-Hyung Lee, Je-Tae Woo… in Biotechnology and Bioprocess Engineering (2019)

41.Effect of magnolol on cerebral injury and blood brain barrier dysfunction induced by ischemia-reperfusion in vivo and in vitro
Magnolol, a neolignan compound isolated from traditional Chinese...Magnolia officinalis..., has a potentially therapeutic influence on ischemic stroke. Previous studies have demonstrated that cerebral ischemia-re...

Xiaoyan Liu, Xiaoling Chen, Yuanjun Zhu, Kewei Wang, Yinye Wang in Metabolic Brain Disease (2017)

42.Synergistic effect of lysozyme on bactericidal activity of magnolol and honokiol against a cariogenic bacterium,Streptococcus mutans OMZ 176
A combination of magnolol or honokiol with lysozyme isolated from the...Streptococcus mutans OMZ 176. The synergistic ratio increased with time dependence.

Kihwan Bae, Hongrock Oh in Archives of Pharmacal Research (1990)

43.The absorption and transport of magnolol in Caco-2 cell model
To investigate the absorption and transport mechanism of magnolol in Caco-2 cell model.

An-guo Wu 吴安国, Bao Zeng 曾 宝, Meng-qiu Huang 黄孟秋… in Chinese Journal of Integrative Medicine (2013)

44.Separation and determination of magnolol and honokiol inMagnolia officinalis bark by capillary zone electrophoresis
The effects of pH on separation parameters such as migration mobility, resolution, sensitivity, column efficiency and peak shape were emphatically studied. Better separation of magnolol and honokiol using capilla...

Ziping Zhang, Zhide Hu, Gengliang Yang in Microchimica Acta (1997)

45.Preparation and Property Analysis of Natural Antibacterial Agents-Magnolol and Chitosan-Based Antibacterial Wrapping Paper
In this paper, chitosan and magnolol and their compound were used as antibacterial ... to compare the antibacterial effects of chitosan and magnolol, The preservation effect of antibacterial wrapping paper ... re...

Yan Zhang, Deshui Li, Qingbao Wei in Advanced Graphic Communication, Printing a… (2020)

46.Anti-inflammatory and analgesic effects of magnolol
Magnolol, isolated from Magnolia officinalis..., inhibited mouse hind-paw edema induced by carrageenan, compound 4880, polymyxin B and reversed passive Arthus reaction. Acetic acid-induced writhing response was d...

Jih-Pyang Wang, Mei-Feng Hsu… in Naunyn-Schmiedeberg's Archives of Pharmaco… (1992)

47.Synthesis of 1-[3-(N-pyrrole)propyl]-3-[1-tert-butoxycarbonylamino-propyl]-imidazolium tetrafluoroborate ionic liquid for application in electrochemical sensing of magnolol
...1-[3-(N-Pyrrole)propyl]-3-[1-tert-butoxy-carbonylamino-propyl]imidazolium tetrafluoroborate ionic liquid was successfully synthesized and characterized. The ionic liquid was electrochemically polymerized onto ...

Guishen Liu, Yanhui Ma, Xiaodong Hou, Yina huang, Jianpeng Chen, Guoqing Zhan… in Ionics (2015)

48.Mechanistic Evidence to Support the Anti-hepatitis B Viral Activity of Multifunctional Scaffold & Conformationally Restricted Magnolol
Magnolol, phenolic bioactive phytomolecule, is a potential ... mechanistically analyze the probable site of action for magnolol. Magnolol has been docked with EF3-CaM adenylyl ... and clinical development of semi...

Rajeev K. Singla in National Academy Science Letters (2014)

49.High-Performance Thin-Layer Chromatographic-Bioautographic Method for the Simultaneous Determination of Magnolol and Honokiol in Magnoliae officinalis Cortex
A simple and accurate high-performance thin-layer chromatography (HPTLC)-bioautographic method was developed for the quantitative analysis of magnolol and honokiol in the herbal medicine Magnoliae officinalis Cor...

Lihua Gu, Shansong Zheng, Tao Wu… in JPC – Journal of Planar Chromatography – M… (2014)

50.Self-assembly and hydrothermal technique syntheized Fe2O3-RGO nanocomposite: The enhancement effect of electrochemical simultaneous detection of honokiol and magnolol
The nanocomposite of Fe2O3-reduced graphene oxide (Fe2O3-RGO) was synthesized by a hydrothermal reduction using self-assembly of Fe(OH)3...colloidal suspension and graphene oxide (GO) as precursors at 180°C. The ...

Weibing Hu, Wen Zhang, Yan Wu, Wanyun Qu in Journal of Electroceramics (2018)

51.Separation and determination of honokiol and magnolol in herbal medicines by flow injection-capillary electrophoresis
A simple, rapid, and accurate method for the separation and determination of honokiol and magnolol in Magnolia officinalis and related herbal medicines was developed by combination of flow injection (FI) and capi...

Lihong Liu, Xinan Wu, Liuyin Fan, Xingguo Chen… in Analytical and Bioanalytical Chemistry (2006)

52.Honokiol and Magnolol Inhibit CXCL10 and CXCL11 Production in IL-27-Stimulated Human Oral Epithelial Cells
Honokiol and magnolol, which are lignans isolated from Magnolia quinquepeta ... , the anti-inflammatory effects of honokiol and magnolol on periodontal disease are still uncertain. The ... was to examine the effe...

Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo in Inflammation (2018)

53.Protective Effect of Magnolol on Lipopolysaccharide-Induced Acute Lung Injury in Mice
Magnolol, a tradition Chinese herb, displays an ... effects. To investigate the protective effect of magnolol on lipopolysaccharide (LPS)-induced acute lung ... kg). The mice received intratracheal instillation o...

Yun Feng Ni, Tao Jiang, Qing Shu Cheng, Zhong Ping Gu, Yi Fang Zhu… in Inflammation (2012)

54.Antifungal activity of magnolol and honokiol
Two neolignan compounds, magnolol (5,5′-diallyl-2,2′-dihydroxybiphenyl...1) and honokiol (5,5′-diallyl-2,4′-dihydroxybiphenyl,2), were isolated from the stem bark ofMagnolia obovata and evaluated for antifungal a...

Kyu Ho Bang, Yoon Kwan Kim, Byung Sun Min, Min Kyun Na… in Archives of Pharmacal Research (2000)